As I posted earlier, the nightmare called cancer seems to have more treatments! As expected, we know about a lot of medications, and we’ve been using them for all kinds of problems so far, but no one told us that they are curing cancer! Why, well probably because they are cheap and they would not make anyone rich.
It seems that melatonini is one of them and the popular medication has miraculous powers!
“Papers Reviewed:
2023 Sep – Putta et al – Melatonin: Avenues in cancer therapy and its nanotechnological advancements
2023 Jun – Megerian et al – Melatonin and Prostate Cancer: Anti-tumor Roles and Therapeutic Application
2022 Sep – Davoodvandi et al – Melatonin and cancer suppression: insights into its effects on DNA methylation
2022 Aug – Florido et al – Understanding the Mechanism of Action of Melatonin, Which Induces ROS Production in Cancer Cells
2022 May – Monayo et al – The Prospective Application of Melatonin in Treating Epigenetic Dysfunctional Diseases
2022 Mar – Leilei Wang et al – Use of Melatonin in Cancer Treatment: Where Are We?
2021 Jul – Gonzalez et al – Melatonin as an Adjuvant to Antiangiogenic Cancer Treatments
2021 Apr – Talib et al – Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities.”
These are the papers reviewed in the article linked here. All of them present the amazing benefits of melatonin!
Melatonin has a significant impact on tumor initiation, promotion, and progression by regulating multiple signaling pathways. It can inhibit oncogenic miRNAs while enhancing tumor suppressor miRNAs. Also, melatonin can suppress cancer stem cells that cause relapse and metastasis.
Melatonin also influences the tumor microenvironment by shifting the immune system response towards the cytotoxic side. It does this by stimulating the production of cytotoxic T-cells like CD8 cells or NK cells, while inhibiting T regulatory cells (Tregs) and cancer-associated fibroblasts (CAFs) that facilitate immune escape of cancer cells.
Also, melatonin enhances the effects of chemotherapy and reduces its side effects. It sensitizes cancer cells to chemo by promoting apoptosis. It can also enhance the effect of radiation therapy.
We suggest that you take a look at the original piece which addresses all the studies involved.
