Just In: COVID Variants Are Resisting Antibodies From 2nd and 3rd mRNA Vaccines

Just In: COVID Variants Are Resisting Antibodies From 2nd and 3rd mRNA Vaccines

It has been just reported the fact that the COVID variants resist the antibodies coming from the second and third doses of mRNA vaccines. Check out the latest reports about this below.

COVID vaccines in the news again

All COVID-19 variants, including Omicron, show resistance to vaccine-induced antibodies, making them less responsive to the vaccine, according to a study published in the Vaccine journal. However, this resistance can be temporarily overcome with additional COVID-19 shots.

“Our data reflect the poor durability of vaccine-induced nAb (neutralizing antibody) responses,” the study authors wrote.Neutralizing antibodies are produced by the body to prevent the SARS-CoV-2 virus from entering and infecting cells.

In a recent study, researchers collected antibodies from individuals who received three doses of the COVID-19 mRNA vaccines, which included the two primary shots and an additional booster.

The antibodies were then tested against various COVID-19 variants after the second and third doses were administered. It was observed that the vaccine-induced antibodies’ resistance was slightly reduced after the third dose.

Louisiana State University researchers followed 16 uninfected individuals for over 420 days, monitoring their antibodies’ response to COVID-19 viruses before and after vaccination at weekly and monthly intervals.

The participants were administered three doses of a monovalent COVID-19 mRNA vaccine that contained the original Wuhan variant of the virus.

Antibodies were collected three weeks after the second and third doses, which showed strong neutralizing effects against the original Wuhan COVID-19 variant. However, these neutralizing antibodies decreased rapidly, and after the second dose, at four months, and after the third dose, at six months, the levels of these antibodies had fallen back to pre-vaccination levels.

It has been observed that the other variants of COVID-19 are considerably more resistant to antibodies produced after receiving the second and third doses of the vaccine.

Even at three weeks after vaccination, when the antibodies are believed to be the most powerful, the vaccines would have less effect in preventing symptomatic infections caused by these subsequent variants, as compared to the original Wuhan variant.

To counter this, a third dose or booster was administered three to four months after receiving the second mRNA vaccine dose. Surprisingly, the virus’s resistance to the vaccine was slightly reduced after the booster shot was administered, despite the fact that all three doses were the same.

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