Dopamine Deficit Could Be Linked To Early Stages Of Alzheimer’s Disease Development

Dopamine Deficit Could Be Linked To Early Stages Of Alzheimer’s Disease Development

A deficit of dopamine, the neurotransmitter involved in Parkinson’s disease, could also be one of the first signs of an incipient Alzheimer’s disease. At least, that’s what researchers have found during a study carried out at the University of Sheffield and published in the Journal of Alzheimer’s Disease. Besides, the new findings could lead to improved diagnosis of Alzheimer’s in its early stages and to the development of new and more effective Alzheimer’s Disease treatment.

Dopamine is a neurotransmitter that has a series of functions that include the regulation of movement, motivation, reward system, or emotional responses. The loss of neurons that produce it, called dopaminergic, could be the cause of early stages of Alzheimer’s disease.

Experiments conducted on mice prove the researchers’ theory

Recent studies in mouse models for Alzheimer’s disease had shown a significant preclinical loss of dopaminergic neurons in the ventral tegmental area and a reduced innervation of the hippocampus by these neurons that was associated with a decrease in memory.

What the researchers observed was that the size of the ventral tegmental area, where the dopamine is produced, was remarkably associated with the size of the hippocampus and the brain’s memory capabilities.

A deficit of dopamine can lead to the development of the early stages of Alzheimer’s disease

The conclusion reached by Dr. Venneri’s team was that the decrease in dopaminergic activity in the ventral tegmental area may be key in the development of the earliest pathological signs of Alzheimer’s disease.

This finding could suggest new strategies for the early treatment of this devastating pathology for which there is currently no cure or significant way to stabilize it.

If these results will be confirmed, then they could revolutionize the diagnosis of Alzheimer’s disease in its early stages and also could lead to the development of a new more effective Alzheimer’s Disease treatment.

One thought on “Dopamine Deficit Could Be Linked To Early Stages Of Alzheimer’s Disease Development

  1. I was diagnosed five years ago at the age of 51. I had symptoms for 3-4 years prior to that but did not know anything about Parkinson’s. I first noticed a slight twitch in my left hand, finger and thumb, which became pill rolling. We attended a lot of sports events and I would lose my balance in the moving crowd. I then started seeing a neurologist. I started falling a lot when losing my balance and had a hard time walking normal. I finally froze up in the doorway at church. I told my Neuro and he said that I had Parkinson’s. Started me on entacapone,levodopa, carbidopa, and pramipexole and I still didn’t feel or get better January 2017 my neurologist and I decided to go with natural treatment and was introduced to Green House Herbal Clinic natural Parkinson’s disease Herbal formula, i had a total decline of symptoms with this Parkinson’s Herbal formula treatment. Visit Green House Herbal Clinic official web-site ww w. greenhouseherbalclinic. com. The tremors, Shaking, Joint Stiffness and other symptoms has subsided.  I am very pleased with this treatment. I feel very well now and exercise regularly, sometimes i totally forget i ever had Parkinson’s,Don’t give up hope, fellow sufferers. Share with friends!!

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