It has been just revealed the fact that there is an amazing discovery that has been made by experts that can slow aging. Check out the details that we are revealing below in order to find out what this is.
New ways to slow aging have been revealed
It’s understandable that scientists have been concerned about aging and how to prevent it for a long time. Fortunately, a recent study published in the journal EMBO Reports has uncovered a crucial repair pathway that helps prevent cells from aging prematurely.
Our cells are like tiny factories that need to be in top shape to keep us healthy. Luckily, they have lysosomes- internal garbage disposal stations- to break down cellular debris.
Microautophagy is a cellular process where worn-out components are broken down, while autophagy can destroy entire cells.
However, it is important to note that if the lysosome, an organelle responsible for breaking down waste materials, becomes damaged or worn out, the enzymes it contains may leak and digest healthy cellular machinery.
This can result in inflammation and ultimately, cell death. Therefore, it is crucial to maintain the lysosomes in good condition to prevent such damage.
In a recent study, researchers discovered that lysosomes have the ability to repair themselves through a process called microautophagy.
Gamma-aminobutyric acid receptor-associated proteins (GABARAPs) are responsible for recruiting the damaged lysosome’s membrane to the site of injury.
These proteins then assemble the ESCRT cellular repair machinery, which leads to the folding of the damaged area on the lysosomal membrane. In turn, lysosomes can break down their own damaged components.
Once the repair job is complete, a protein called Serine-threonine kinase 38, or STK38, comes in to help disassemble the repair machinery.
Experts have discovered the fact that by removing these signaling molecules, cells begin to age much faster, shortening the lifespan of their host animal (which, in the case of this study, was a microscopic worm called C. elegans).
