New reports reveal the fact that rice bran-derived nanoparticles are showing impressive anti-cancer properties. Check out the latest reports about this below, as the subject holds great importance for the medical industry,
New study shows the connection between nanoparticles and anti-cancer effects
A recent study published in the Journal of Nanobiotechnology (JN) has shown that nanoparticles derived from rice bran (rbNPs) have great potential for anti-cancer activity in mice. Furthermore, rbNPs do not appear to be toxic to noncancerous cells, which is a positive sign.
However, it is important to note that while the researchers have described the anti-cancer effect as “strong,” further clinical trials are required to determine if rbNPs have a similar benefit in humans.
Rice bran is a byproduct of the rice milling process that is typically discarded during manufacturing.
It has been found to contain essential nutrients such as vitamins, minerals, proteins, and fatty acids, as well as compounds with anti-cancer properties such as γ-oryzanol, γ-tocotrienol, and tricin.
Nanoparticles, which are tiny particles used to deliver substances to tissues, have been identified as a potential means of utilizing the therapeutic value of rice bran nanoparticles (rbNPs) for cancer treatment.
The JN study, which was conducted in Japan, hypothesized that rbNPs may have substantial therapeutic value for cancer treatment.
After administering rbNPs to mice with colon26 cancer, the researchers noticed a significant reduction in cell division and an increase in apoptosis, which indicates that rbNPs possess potent anti-cancer properties.
Moreover, the expression of proteins such as β-catenin, which is involved in cell proliferation, and cyclin D1, which is involved in cancer metastasis, was decreased.
According to the JN study, rbNPs have shown greater anti-cancer activity than other plant-derived nanoparticles (pdNPs) derived from grapes, ginger, and lemon.
While ginger and lemon had a significant impact on reducing the number of colon26 cells at high concentrations, rbNPs were found to be the most effective in decreasing colon26 cells at all concentrations.
For more details, check out the original study.